The Rise of Infusions: Prime IV Hydration & Wellness Franchise

Prime IV franchise business
Deborah Pratt

Founder and CEO Amy Neary Explains the Benefits of IV Therapy 

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The wellness industry is booming, says Amy Neary (above), founder and CEO of the Prime IV Hydration & Wellness franchise, as people choose to be more proactive and take control of their health. “And IV therapy is at the forefront, providing a unique, high-demand service,” she says. “IV therapy offers quick and efficient hydration, nutrient delivery and recovery benefits that align with the fast-paced lifestyle of many individuals.”

With IV therapy, vitamins, minerals and amino acids are delivered directly into the bloodstream, which allows for 100 percent absorption. At Prime IV, treatments are administered by licensed medical professionals using high-quality ingredients in a relaxing setting to ensure safety and comfort. “We continuously monitor and review our procedures, staying updated with the latest industry standards and medical advancements to provide safe and effective treatments for our clients,” Neary says.

The Benefits of IV Therapy

Each infusion is customized to the individual after consultations on the person’s needs and health. Treatments are targeted to rehydrate, boost immunity, enhance athletic performance, assist with weight loss, or promote overall vitality, among other benefits, or to alleviate specific conditions, including seasonal allergies, altitude sickness, arthritis, jet lag, migraines or cold and flu. “Increased awareness and education around the benefits of IV therapy, supported by positive testimonials and endorsements, have made it a mainstream wellness solution for a growing body of the population,” Neary says. 

Since its beginning in 2017, Prime IV has flourished, becoming the fastest-growing IV therapy franchise in the country, with more than 125 locations nationwide. 

“Prime IV evolved through a combination of strategic planning, continuous innovation, and an unwavering commitment to quality and customer service,” Neary says. “Our growth strategy focused on expanding our franchise network, ensuring each new location adheres to our high standards. We also invested in cutting-edge wellness solutions like peptide therapy, enhancing our service offerings.” She also credits Prime IV leadership’s deep knowledge of the franchising system and willingness to engage regularly with franchisees along with a strong marketing strategy. 

Prime IV franchise business

The company’s success has been recognized with six major awards this year alone. Entrepreneur Magazine ranked Prime IV as No. 1 in the IV Therapy category and No. 17 out of 150 in the New and Emerging Franchises category. The magazine also named the brand to the Franchise 500 list, as No. 389, and to the Fastest Growing Franchise list, as No. 132. The Entrepreneur rankings are based on dozens of data points, including costs, size and growth, franchisee support, brand reputation and financial stability. 

In addition, Franchise Business Review named Prime IV to the Culture 100 Awards, which recognize brands that prioritize culture and franchisee experience, and also chose the company as part of its Top 200 Franchises list, which is based on franchisee feedback. And in 2023, the company was selected as one of only 50 franchises to qualify as a Top Franchise for Woman. 

“Receiving multiple awards in 2024 is a testament to our dedication to excellence and innovation in the wellness industry,” Neary says. “These accolades validate our business model and underscore the hard work and commitment of our team and franchisees. They enhance our credibility and brand reputation, attracting more potential franchisees and customers.”

Franchisee Training

Prime IV franchise business

New Prime IV franchisees are trained during a thorough onboarding program, which includes information on operational procedures, customer service and marketing strategies. Support continues after a franchise opens, with ongoing training and a mentorship program. “Our comprehensive training and support system ensures franchisees have the tools and knowledge to succeed,” Neary says, along with open communication with corporate staff “to ensure franchisees feel supported and equipped to thrive in their business.”

Neary is confident that her company will continue to grow along with the market for IV therapy. “The global IV therapy market is projected to reach $19.6 billion by 2027,” she says, “driven by the increasing awareness of its benefits and rising demand for wellness services.” As part of that growth, Prime IV is looking to expand its range of services, she says, and is testing a new platform and a product that is scheduled to launch later this year. 

“At Prime IV, we are positioning ourselves ahead by continuously expanding our service offerings to include cutting-edge treatments like peptide therapy and NAD+ infusions,” Neary says. “We are also exploring digital health tools to enhance customer experience and engagement. Our commitment to research and development ensures that we stay at the forefront of industry innovations, allowing us to offer the most effective and personalized wellness solutions to our clients.”

For more information about Prime IV, visit https://www.franchising.primeivhydration.com/.

© Copyright FranchiseWire 2026
Deborah Pratt

Deborah Pratt

Deborah Pratt is an experienced writer and editor. She began her career working for newspapers, including the Abilene Reporter-News, as a copy editor, news editor and page designer and won awards from the Texas AP Managing Editors association for page design.

She served as Projects Editor for Design NJ magazine, where she edited articles and wrote about all things related to home design in New Jersey: from trends in furnishings and decorating ideas to landscaping and renovation projects. For 16 years, she worked as a senior editor at Educational Testing Service and edited testing materials for high-stakes assessments along with research reports and test-preparation documents.

As a freelancer, she has written for publications including Scout Life (formerly Boys' Life) magazine and The Times of Trenton, with articles on recreation, parenting, travel and other lifestyle issues. She has edited for publishers including McGraw Hill, primarily on education-related topics. She is a member of the Editorial Freelancers Association, an organization dedicated to supporting freelancers through opportunities for professional development and networking.

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